The current investigation was conducted to rigorously address these important methodological concerns and to develop standardized methods that can be used to identify the DMN during the collection of resting state FMRI data. Specifically, several important questions remain regarding the consistency and reliability of the DMN over time, the analytic techniques used to characterize the brain at rest, and how reliable human and automated methods are in selecting DMN activity.
Although the existence of the DMN has been investigated using multiple imaging modalities including FMRI, PET, and EEG, controversy remains regarding the significance and applicability of the DMN model from both conceptual and quantitative perspectives. In particular, there has been increasing interest in the concept of a default mode network (DMN), which exhibits coherent fluctuations during passive mental activity, becomes deactivated during more demanding cognitive tasks, and which may serve as an intrinsic baseline state. INTRODUCTION With the advent of advanced neuroimaging techniques such as functional magnetic resonance imaging (FMRI) and the arrival of increasingly sophisticated methods for interpreting these data, the study of the human brain at rest has flourished in recent years. Interrater and intermethod reliability of default mode network selection Interrater and intermethod reliability of default mode network selectionįranco, Alexandre R.